Driver's eye gaze holds a wealth of cognitive and intentional cues crucial for intelligent vehicles. Despite its significance, research on in-vehicle gaze estimation remains limited due to the scarcity of comprehensive and well-annotated datasets in real driving scenarios. In this paper, we present three novel elements to advance in-vehicle gaze research. Firstly, we introduce IVGaze, a pioneering dataset capturing in-vehicle gaze, compiled from 125 individuals and covering a large range of gaze and head within vehicles. Conventional gaze collection systems are inadequate for in-vehicle use. In this dataset, we propose a new vision-based solution for in-vehicle gaze collection, introducing a refined gaze target calibration method to tackle annotation challenges. Second, our research focuses on in-vehicle gaze estimation leveraging the IVGaze. Images of in-vehicle faces often suffer from low resolution, prompting our introduction of a gaze pyramid transformer that harnesses transformer-based multilevel features integration. Expanding upon this, we introduce the dual-stream gaze pyramid transformer (GazeDPTR). Employing perspective transformation, we rotate virtual cameras to normalize images, utilizing camera pose to merge normalized and original images for accurate gaze estimation. GazeDPTR showcases state-of-the-art performance on the IVGaze dataset. Thirdly, we explore a novel strategy for gaze zone classification by extending the GazeDPTR. A foundational tri-plane and project gaze onto these planes are newly defined. Leveraging both positional features from the projection points and visual attributes from images, we achieve superior performance compared to relying solely on visual features, thereby substantiating the advantage of gaze estimation. To foster advancements in this domain, the code and dataset will be released to facilitate future research.